| Name | H 89 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2485 |
| Prices | $89.00, $185.00, $755.00 |
| Sizes | 1 mg, 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 130964-39-5 |
| Chemical Name | N-[2-[[3-(4-Bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamidedihydrochloride |
| Formula | C20H20BrN3O2S.2HCl |
| Molecular Weight | 519.28 |
| Purity | >98 % |
| Description | Protein kinase A inhibitor that also inhibits several other kinases (IC 50 values are 80, 120, 135, 270, 2600 and 2800 nM for S6K1, MSK1, PKA, ROCKII, PKB α and MAPKAP-K1b). Exhibits antinociceptive activity. Also available as part of the PKA Tocriset TM . |
| Supplier Page | Shop |
Lochner A, Moolman JA. Cardiovasc Drug Rev. 2006 Fall-Winter;24(3-4):261-74.
Yamada K, Inoue H, Kida S, Masushige S, Nishiyama T, Mishima K, Saito I. Pathobiology. 2006;73(1):1-7.