H-9 dihydrochloride

Name H-9 dihydrochloride
Supplier Tocris Bioscience
Catalog 0542
Prices $115.00, $485.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 116700-36-8
Chemical Name N-(2-Aminoethyl)-5-isoquinolinesulfonamidedihydrochloride
Formula C11H13N3O2S.2HCl
Molecular Weight 324.22
Purity >99 %
Description Protein kinase inhibitor. Inhibits PKA (K i = 1.9 μ M), PKG (K i = 0.9 μ M), CaMK II (K i = 60 μ M), PKC (K i = 18 μ M), casein kinase I (K i = 110 μ M) and casein kinase II (K i > 300 μ M).
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Product References

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide - Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide

Hidaka H, Inagaki M, Kawamoto S, Sasaki Y. Biochemistry. 1984 Oct 9;23(21):5036-41.

Pharmacology of protein kinase inhibitors. - Pharmacology of protein kinase inhibitors.

Hidaka H, Kobayashi R. Annu Rev Pharmacol Toxicol. 1992;32:377-97.