( R )-(+)-HA-966

• Supplier: Tocris Bioscience
• Catalog: 1541
• Prices: $139.00
• Sizes: 10 mg
• Function Type: Antagonist
• Cas Number: 123931-04-4
• Chemical Name: (R)-(+)-3-Amino-1-hydroxypyrrolidin-2-one
• Formula: C4H8N2O2
• Molecular Weight: 116.12
• Purity: >98 %
• Description: Antagonist/partial agonist at the glycine site of the NMDA receptor; able to cross the blood-brain barrier. Also available as part of the NMDA Receptor - Glycine Site Tocriset™ . S-enantiomer (Cat. No. 0282) available.

Product References

Stereoselectivity for the (R)-enantiomer of HA-966 - Stereoselectivity for the (R)-enantiomer of HA-966

Pullan LM, Britt M, Chapdelaine MJ, Keith RA, LaMonte D, Mangano TJ, Patel J, Powel RJ, Stumpo RJ, Warwick PJ, et al.. J Neurochem. 1990 Oct;55(4):1346-51.

Effects of (+)-HA-966 and 7-chlorokynurenic acid on the kinetics of - Effects of (+)-HA-966 and 7-chlorokynurenic acid on the kinetics of

Kemp JA, Priestley T. Mol Pharmacol. 1991 May;39(5):666-70.

Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one - Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one

Pullan LM, Verticelli AM, Paschetto KA. Eur J Pharmacol. 1991 Sep 12;208(1):25-9.