( S )-(-)-HA-966

• Supplier: Tocris Bioscience
• Catalog: 0281
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Cas Number: 111821-58-0
• Chemical Name: (S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one
• Formula: C4H8N2O2
• Molecular Weight: 116.12
• Purity: >98 %
• Description: Possesses potent sedative and ataxic action, probably through disruption of striatal dopaminergic mechanisms. R-enantiomer (Cat. No. 0281) also available.

Product References

Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central - Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central

Singh L, Donald AE, Foster AC, Hutson PH, Iversen LL, Iversen SD, Kemp JA, Leeson PD, Marshall GR, Oles RJ, et al.. Proc Natl Acad Sci U S A. 1990 Jan;87(1):347-51.

(+-)-1-hydroxy-3-aminopyrrolidone-2 (HA-966) inhibits the activity of substantia - (+-)-1-hydroxy-3-aminopyrrolidone-2 (HA-966) inhibits the activity of substantia

Shepard PD, Lehmann H. J Pharmacol Exp Ther. 1992 May;261(2):387-94.

Responses of rat substantia nigra dopamine-containing neurones to (-)-HA-966 in - Responses of rat substantia nigra dopamine-containing neurones to (-)-HA-966 in

Grobaski KC, Ping H, daSilva HM, Bowery NG, Connelly ST, Shepard PD. Br J Pharmacol. 1997 Feb;120(4):575-80.