HC 030031

Name HC 030031
Supplier Tocris Bioscience
Catalog 4285
Prices $139.00, $585.00
Sizes 10 mg, 50 mg
Function Type Blocker
Cas Number 349085-38-7
Chemical Name 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide
Formula C18H21N5O3
Molecular Weight 355.39
Purity >99 %
Description Selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx (IC 50 values are 6.2 and 5.3 μ M respectively). Does not block currents mediated by TRPV1, TRPV3, TRPV4, hERG or Na V 1.2 channels. Inhibits AITC- and formalin-induced flinching in vivo .
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