Name | HC 030031 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4285 |
Prices | $139.00, $585.00 |
Sizes | 10 mg, 50 mg |
Function Type | Blocker |
Cas Number | 349085-38-7 |
Chemical Name | 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide |
Formula | C18H21N5O3 |
Molecular Weight | 355.39 |
Purity | >99 % |
Description | Selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx (IC 50 values are 6.2 and 5.3 μ M respectively). Does not block currents mediated by TRPV1, TRPV3, TRPV4, hERG or Na V 1.2 channels. Inhibits AITC- and formalin-induced flinching in vivo . |
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