| Name | HC 067047 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2896 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 883031-03-6 |
| Chemical Name | 2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide |
| Formula | C26H28F3N3O2 |
| Molecular Weight | 471.51 |
| Purity | >99 % |
| Description | Potent and selective TRPV4 antagonist. Reversibly inhibits currents through mouse, human and rat TRPV4 orthologs (IC 50 values are 17, 48 and 133 nM respectively). Also inhibits the endogenous TRPV4-mediated response to 4 α -PDH (IC 50 = 22 nM). Selective for TRPV4 over TRPV1, TRPV2, TRPV3 and TRPM8 channels. |
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