| Name | HDS 029 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4100 |
| Prices | $105.00, $225.00 |
| Sizes | 1 mg, 10 mg |
| Function Type | Inhibitor |
| Cas Number | 881001-19-0 |
| Chemical Name | N-(4-[(-3-Chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl-2-butynamide |
| Formula | C17H11ClFN5O |
| Molecular Weight | 355.76 |
| Purity | >97 % |
| Description | Potent inhibitor of the ErbB receptor family (IC 50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively). Inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells (IC 50 values are 2.5 and 24 nM respectively). |
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