Hemokinin 1 (mouse)

• Supplier: Tocris Bioscience
• Catalog: 2576
• Prices: $209.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 208041-90-1
• Formula: C61H100N22O15S
• Molecular Weight: 1413.66
• Description: Novel mammalian endogenous peptide, homolog of substance P, that is a high affinity and selective agonist at the tachykinin NK 1 receptor (K i values are 0.175 and 560 nM for NK 1 and NK 2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo .

Product References

Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. - Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis.

Zhang Y, Lu L, Furlonger C, Wu GE, Paige CJ. Nat Immunol. 2000 Nov;1(5):392-7.

Hemokinin 1 is a full agonist at the substance P receptor. - Hemokinin 1 is a full agonist at the substance P receptor.

Morteau O, Lu B, Gerard C, Gerard NP. Nat Immunol. 2001 Dec;2(12):1088.

Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. - Pharmacological profile of the novel mammalian tachykinin, hemokinin 1.

Bellucci F, Carini F, Catalani C, Cucchi P, Lecci A, Meini S, Patacchini R, Quartara L, Ricci R, Tramontana M, Giuliani S, Maggi CA. Br J Pharmacol. 2002 Jan;135(1):266-74.