Hemopressin (rat)

• Supplier: Tocris Bioscience
• Catalog: 3791
• Prices: $329.00
• Sizes: 1 mg
• Cas Number: 568588-77-2
• Formula: C53H77N13O12
• Molecular Weight: 1088.27
• Description: Bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. K i values are 27.76, 3.43 and 1.87 μ M respectively. Potent hypotensive in vivo . Also acts as a selective CB 1 receptor inverse agonist. Displays antinociceptive activity and induces hypophagia in vivo .

Product References

Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and - Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and

Rioli V, Gozzo FC, Heimann AS, Linardi A, Krieger JE, Shida CS, Almeida PC, Hyslop S, Eberlin MN, Ferro ES. J Biol Chem. 2003 Mar 7;278(10):8547-55. Epub 2002 Dec 24.

Hemopressin is an inverse agonist of CB1 cannabinoid receptors. - Hemopressin is an inverse agonist of CB1 cannabinoid receptors.

Heimann AS, Gomes I, Dale CS, Pagano RL, Gupta A, de Souza LL, Luchessi AD, Castro LM, Giorgi R, Rioli V, Ferro ES, Devi LA. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20588-93. Epub 2007 Dec 12.

The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food - The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food

Dodd GT, Mancini G, Lutz B, Luckman SM. J Neurosci. 2010 May 26;30(21):7369-76.