HexylHIBO

Name HexylHIBO
Supplier Tocris Bioscience
Catalog 0526
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 334887-43-3
Chemical Name α-Amino-4-hexyl-2,3-dihydro-3-oxo-5-isoxazolepropanoicacid
Formula C12H20N2O4
Molecular Weight 256.3
Purity >98 %
Description Group I mGlu receptor antagonist (K i values are 140 and 110 μ M at mGlu 1a and mGlu 5a receptors respectively). Decreases sEPSCs in rat pyramidal neurons in vitro .
Supplier Page Shop

Product References

Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists - Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists

Madsen U, Brauner-Osborne H, Frydenvang K, Hvene L, Johansen TN, Nielsen B, Sanchez C, Stensbol TB, Bischoff F, Krogsgaard-Larsen P. J Med Chem. 2001 Mar 29;44(7):1051-9.

Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal - Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal

Bandrowski AE, Huguenard JR, Prince DA. J Neurophysiol. 2003 Mar;89(3):1308-16.