Honokiol

• Supplier: Tocris Bioscience
• Catalog: 2875
• Prices: $75.00, $309.00
• Sizes: 10 mg, 50 mg
• Function Type: Antioxidant
• Cas Number: 35354-74-6
• Chemical Name: 5,3'-Diallyl-2,4'-dihydroxybiphenyl
• Formula: C18H18O2
• Molecular Weight: 266.33
• Purity: >98 %
• Description: Anti-inflammatory, antioxidant, antitumor and antiangiogenic agent. Blocks NF- κ B activation by a variety of stimuli, including TNF and okadaic acid. Shown to scavenge superoxide and peroxyl radicals. Also inhibits a variety of inflammatory responses. Reverses cardiac hypertrophy in mice via SIRT3 activation.

Product References

Honokiol, a small molecular weight natural product, inhibits angiogenesis in - Honokiol, a small molecular weight natural product, inhibits angiogenesis in

Bai X, Cerimele F, Ushio-Fukai M, Waqas M, Campbell PM, Govindarajan B, Der CJ, Battle T, Frank DA, Ye K, Murad E, Dubiel W, Soff G, Arbiser JL. J Biol Chem. 2003 Sep 12;278(37):35501-7. Epub 2003 Jun 19.

Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits - Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits

Ahn KS, Sethi G, Shishodia S, Sung B, Arbiser JL, Aggarwal BB. Mol Cancer Res. 2006 Sep;4(9):621-33.

Honokiol is a potent scavenger of superoxide and peroxyl radicals. - Honokiol is a potent scavenger of superoxide and peroxyl radicals.

Dikalov S, Losik T, Arbiser JL. Biochem Pharmacol. 2008 Sep 1;76(5):589-96.

Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression. - Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression.

Kim BH, Cho JY. Acta Pharmacol Sin. 2008 Jan;29(1):113-22.