Huwentoxin XVI

• Supplier: Tocris Bioscience
• Catalog: 4718
• Prices: $265.00
• Sizes: 100 µg
• Function Type: Blocker
• Cas Number: 1600543-88-1
• Formula: C196H292N50O56S6
• Molecular Weight: 4437.13
• Description: Potent and selective N-type Ca 2+ channel blocker (IC 50 ~ 60 nM); selectively and reversibly blocks N-type Ca 2+ channels. Does not block T-type Ca 2+ channels, K + channels or Na + channels. Exhibits analgesic effects in vivo .

Product References

Venomics of the spider Ornithoctonus huwena based on transcriptomic versus - Venomics of the spider Ornithoctonus huwena based on transcriptomic versus

Jiang L, Zhang D, Zhang Y, Peng L, Chen J, Liang S. Comp Biochem Physiol Part D Genomics Proteomics. 2010 Jun;5(2):81-8. doi:

Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel - Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel

Deng M, Luo X, Xiao Y, Sun Z, Jiang L, Liu Z, Zeng X, Chen H, Tang J, Zeng W, Songping Liang. Neuropharmacology. 2014 Apr;79:657-67.