Hydroxychloroquine sulfate

• Supplier: Tocris Bioscience
• Catalog: 0183
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 747-36-4
• Chemical Name: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanolsulfate
• Formula: C18H28ClN3O5S
• Molecular Weight: 433.95
• Purity: >99 %
• Description: Autophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro . Also inhibits TLR9.

Product References

Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and - Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and

Lamphier M, Zheng W, Latz E, Spyvee M, Hansen H, Rose J, Genest M, Yang H, Shaffer C, Zhao Y, Shen Y, Liu C, Liu D, Mempel TR, Rowbottom C, Chow J, Twine NC, Yu M, Gusovsky F, Ishizaka ST. Mol Pharmacol. 2014 Mar;85(3):429-40.

Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. - Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells.

Lee HO, Mustafa A, Hudes GR, Kruger WD. PLoS One. 2015 Jul 2;10(7):e0131464.