( R )-(+)-8-Hydroxy-DPAT hydrobromide

Name ( R )-(+)-8-Hydroxy-DPAT hydrobromide
Supplier Tocris Bioscience
Catalog 2547
Prices $159.00, $665.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 78095-19-9
Chemical Name (2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralinhydrobromide
Formula C16H25NO.HBr
Molecular Weight 328.29
Purity >99 %
Description Full 5-HT 1A serotonin receptor agonist; more active enantiomer. Reduces hippocampal 5-HT levels following systemic administration in rats in vivo . More active enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529). 7-Hydroxy-DPAT hydrobromide (Cat. No. 0706) also available.
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Product References

Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions - Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions

Bjork L, Hook BB, Nelson DL, Anden NE, Hacksell U. J Med Chem. 1989 Apr;32(4):779-83.

Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and - Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and

Cornfield LJ, Lambert G, Arvidsson LE, Mellin C, Vallgarda J, Hacksell U, Nelson DL. Mol Pharmacol. 1991 Jun;39(6):780-7.

Differential effects of (R)-, (R, S)- and - Differential effects of (R)-, (R, S)- and

Yoshitake T, Kehr J. Life Sci. 2004 Apr 23;74(23):2865-75.