Name | ( R )-2-Hydroxyglutaric acid disodium salt |
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Supplier | Tocris Bioscience |
Catalog | 0529 |
Prices | $99.00 |
Sizes | 50 mg |
Cas Number | 103404-90-6 |
Chemical Name | (R)-2-Hydroxypentanedioicaciddisodiumsalt |
Formula | C5H6Na2O5 |
Molecular Weight | 192.08 |
Description | Oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF- κ B in bone marrow stromal cells. |
Supplier Page | Shop |