( R )-2-Hydroxyglutaric acid disodium salt

Name ( R )-2-Hydroxyglutaric acid disodium salt
Supplier Tocris Bioscience
Catalog 0529
Prices $99.00
Sizes 50 mg
Cas Number 103404-90-6
Chemical Name (R)-2-Hydroxypentanedioicaciddisodiumsalt
Formula C5H6Na2O5
Molecular Weight 192.08
Description Oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF- κ B in bone marrow stromal cells.
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