IB-MECA

• Supplier: Tocris Bioscience
• Catalog: 4650
• Prices: $199.00, $825.00
• Sizes: 5 mg, 25 mg
• Function Type: Agonist
• Cas Number: 152918-18-8
• Chemical Name: 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide
• Formula: C18H19IN6O4
• Molecular Weight: 510.29
• Purity: >97 %
• Description: Potent and selective A 3 adenosine receptor agonist (K i values are 1.1, 54 and 56 nM for A 3 , A 1 and A 2A receptors respectively). Cardioprotective, reduces infarct size upon reperfusion in rats.

Product References

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as - Structure-activity relationships of N6-benzyladenosine-5'-uronamides as

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Adenosine receptors and their ligands. - Adenosine receptors and their ligands.

Klotz KN. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):382-91.

N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide confers cardioprotection at - N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide confers cardioprotection at

Park SS, Zhao H, Jang Y, Mueller RA, Xu Z. J Pharmacol Exp Ther. 2006 Jul;318(1):124-31. Epub 2006 Apr 12.