I-BRD9

Name I-BRD9
Supplier Tocris Bioscience
Catalog 0748
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1714146-59-4
Chemical Name 5-Ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
Formula C22H22F3N3O3S2
Molecular Weight 497.55
Purity >98 %
Description Potent and selective BRD9 inhibitor (pIC 50 = 7.3). Exhibits >70-fold selectivity for BRD9 over a panel of 34 other bromodomains and >700-fold selectivity over the BET family. Downregulates CLEC 1, DUSP6 , FES and SAMSN 1 genes in Kasumi-1 cells.
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Product References

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