| Name | ICA 121431 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4950 |
| Prices | $179.00, $745.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 313254-51-2 |
| Chemical Name | α-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide |
| Formula | C23H19N3O3S2 |
| Molecular Weight | 449.55 |
| Purity | >98 % |
| Description | Potent and selective inhibitor of human Na V 1.3 and Na V 1.1 channels (IC 50 values are 13 and 23 nM respectively). Exhibits up to 1,000 fold selectivity against other TTX-sensitive or resistant sodium channels (IC 50 values are >10 μ M for human Na V 1.5 and Na V 1.8 channels). Interacts with an inhibitory interaction site distinct from those bound by TTX and local anesthetic-like modulators. |
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