ICI 174,864

• Supplier: Tocris Bioscience
• Catalog: 0833
• Prices: $139.00, $585.00
• Sizes: 1 mg, 5 mg
• Function Type: Antagonist
• Cas Number: 89352-67-0
• Formula: C38H53N5O7
• Molecular Weight: 691.87
• Description: Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.

Product References

ICI 174864: a highly selective antagonist for the opioid delta-receptor. - ICI 174864: a highly selective antagonist for the opioid delta-receptor.

Cotton R, Giles MG, Miller L, Shaw JS, Timms D. Eur J Pharmacol. 1984 Jan 27;97(3-4):331-2.

Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin. - Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin.

Cowan A, Zhu XZ, Porreca F. Neuropeptides. 1985 Feb;5(4-6):311-4.

Studies in vitro with ICI 174,864, [D-Pen2, D-Pen5]-enkephalin (DPDPE) and - Studies in vitro with ICI 174,864, [D-Pen2, D-Pen5]-enkephalin (DPDPE) and

Hirning LD, Mosberg HI, Hurst R, Hruby VJ, Burks TF, Porreca F. Neuropeptides. 1985 Feb;5(4-6):383-6.

Opioid agonist activity of ICI 174864 and its carboxypeptidase degradation - Opioid agonist activity of ICI 174864 and its carboxypeptidase degradation

Cohen ML, Shuman RT, Osborne JJ, Gesellchen PD. J Pharmacol Exp Ther. 1986 Sep;238(3):769-72.