ICI 192,605

• Supplier: Tocris Bioscience
• Catalog: 0836
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 117621-64-4
• Chemical Name: 4-(Z)-6-(2-o-Chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl)hexenoicacid
• Formula: C22H23ClO5
• Molecular Weight: 402.87
• Purity: >98 %
• Description: Potent thromboxane A 2 receptor (TP receptor) antagonist. Competitively inhibits contractile responses to U 46619 (Cat. No. 1932).

Product References

The synthesis of a novel thromboxane receptor antagonist - The synthesis of a novel thromboxane receptor antagonist

Brewster AG, Brown GR, Foubister AJ, Jessup R, Smithers MJ. Prostaglandins. 1988 Aug;36(2):173-8.

Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway - Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway

Arakawa H, Lotvall J, Kawikova I, Lofdahl CG, Skoogh BE. Br J Pharmacol. 1993 Sep;110(1):127-32.

Thromboxane A2 (TP) receptor in the non-pregnant porcine myometrium and its role - Thromboxane A2 (TP) receptor in the non-pregnant porcine myometrium and its role

Cao J, Wakatsuki A, Yoshida M, Kitazawa T, Taneike T. Eur J Pharmacol. 2004 Feb 6;485(1-3):317-27.