| Name | iCRT 14 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1531 |
| Prices | $195.00, $805.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 677331-12-3 |
| Chemical Name | 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion |
| Formula | C21H17N3O2S |
| Molecular Weight | 375.44 |
| Purity | >99 % |
| Description | Potent inhibitor of β -catenin-responsive transcription (CRT) (IC 50 = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between β -catenin and TCF4. Induces marked G 0 /G 1 cell cycle arrest in HCT-116 and HT29 cell lines. |
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