Idazoxan hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3853
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 79944-56-2
• Chemical Name: 2-(1,4-Benzodioxan-2-yl)-2-imidazolinehydrochloride
• Formula: C11H12N2O2.HCl
• Molecular Weight: 240.69
• Purity: >98 %
• Description: α 2 -adrenoceptor antagonist, and I 2 ligand, selective over I 1 sites (pK i values are 5.90, 7.22, 8.01, 7.43, and 7.7 for I 1 , I 2 , α 2A , α 2B , and α 2C receptors respectively).

Product References

Idazoxan: a novel pharmacological tool for the study of alpha 2-adrenoceptors. - Idazoxan: a novel pharmacological tool for the study of alpha 2-adrenoceptors.

Dabire H. J Pharmacol. 1986 Apr-Jun;17(2):113-8.

Keeping an eye on the I site: imidazoline-preferring receptors. - Keeping an eye on the I site: imidazoline-preferring receptors.

Michel MC, Ernsberger P. Trends Pharmacol Sci. 1992 Oct;13(10):369-70.

Evidence for two different imidazoline sites on pancreatic B cells and vascular - Evidence for two different imidazoline sites on pancreatic B cells and vascular

Berdeu D, Gross R, Puech R, Loubatieres-Mariani MM, Bertrand G. Eur J Pharmacol. 1995 Feb 24;275(1):91-8.

'Seeing through a glass darkly': casting light on imidazoline 'I' sites. - 'Seeing through a glass darkly': casting light on imidazoline 'I' sites.

Eglen RM, Hudson AL, Kendall DA, Nutt DJ, Morgan NG, Wilson VG, Dillon MP. Trends Pharmacol Sci. 1998 Sep;19(9):381-90.