Idebenone

• Supplier: Tocris Bioscience
• Catalog: 4016
• Prices: $75.00, $315.00
• Sizes: 10 mg, 50 mg
• Function Type: Antioxidant
• Cas Number: 58186-27-9
• Chemical Name: 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
• Formula: C19H30O5
• Molecular Weight: 338.44
• Purity: >99 %
• Description: Antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitro and in vivo . Inhibits apoptosis of astrocytes via increased NGF production.

Product References

Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review. - Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review.

Zs -Nagy I. Arch Gerontol Geriatr. 1990 Nov-Dec;11(3):177-86.

Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid - Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid

Civenni G, Bezzi P, Trotti D, Volterra A, Racagni G. Eur J Pharmacol. 1999 Apr 9;370(2):161-7.

CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth - CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth

Takuma K, Yoshida T, Lee E, Mori K, Kishi T, Baba A, Matsuda T. Eur J Pharmacol. 2000 Oct 20;406(3):333-9.