IHR 1

Name IHR 1
Supplier Tocris Bioscience
Catalog 2332
Prices $119.00, $505.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 548779-60-8
Chemical Name N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]
Formula C20H12Cl4N2O2
Molecular Weight 454.13
Purity >99 %
Description Potent Smo antagonist (IC 50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro . Fluorescent analog IHR-Cy3 also available.
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