iMDK

• Supplier: Tocris Bioscience
• Catalog: 2611
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Cas Number: 881970-80-5
• Chemical Name: 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one
• Formula: C21H13FN2O2S
• Molecular Weight: 376.4
• Purity: >98 %
• Description: Suppressor of endogenous midkine (MDK) expression. Inhibits PI 3-K signaling in H441 lung adenocarcinoma cells. Selectively attenuates growth of MDK-expressing cancer cells. Induces apoptosis in H441 cells and suppresses growth of H441 cell xenografts in mice.

Product References

Inhibition of the growth factor MDK/midkine by a novel small molecule compound to - Inhibition of the growth factor MDK/midkine by a novel small molecule compound to

Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y. PLoS One. 2013 Aug 16;8(8):e71093.