INCA-6

• Supplier: Tocris Bioscience
• Catalog: 1858
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 3519-82-2
• Chemical Name: 9,10-Dihydro-9,10[1',2']-benzenoanthracene-1,4-dione
• Formula: C20H12O2
• Molecular Weight: 284.31
• Purity: >98 %
• Description: Inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (K d = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT.