Indatraline hydrochloride

Name Indatraline hydrochloride
Supplier Tocris Bioscience
Catalog 4306
Prices $125.00, $535.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 96850-13-4
Chemical Name (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-aminehydrochloride
Formula C16H15Cl2N.HCl
Molecular Weight 328.67
Purity >99 %
Description Potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (K i values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo .
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Product References

Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine, - Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine,

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Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine - Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine

Negus SS, Brandt MR, Mello NK. J Pharmacol Exp Ther. 1999 Oct;291(1):60-9.

Design, synthesis, and monoamine transporter binding site affinities of methoxy - Design, synthesis, and monoamine transporter binding site affinities of methoxy

Gu XH, Yu H, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. J Med Chem. 2000 Dec 14;43(25):4868-76.