2-Iodomelatonin

• Supplier: Tocris Bioscience
• Catalog: 1527
• Prices: $69.00, $259.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 93515-00-5
• Chemical Name: N-[2-(2-Iodo-5-methoxyindol-3-yl)ethyl]acetamide
• Formula: C13H15IN2O2
• Molecular Weight: 358.18
• Purity: >98 %
• Description: Potent melatonin agonist (pK i values are 10.55 and 9.87 at human recombinant MT 1 and MT 2 receptors respectively). 2-[ 125 I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.

Product References

Use of 2-[125I]iodomelatonin to characterize melatonin binding sites in chicken - Use of 2-[125I]iodomelatonin to characterize melatonin binding sites in chicken

Dubocovich ML, Takahashi JS. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3916-20.

Quantitative pharmacological analysis of 2-125I-iodomelatonin binding sites in - Quantitative pharmacological analysis of 2-125I-iodomelatonin binding sites in

Siuciak JA, Krause DN, Dubocovich ML. J Neurosci. 1991 Sep;11(9):2855-64.

Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) - Pharmacological characterization of human recombinant melatonin mt(1) and MT(2)

Browning C, Beresford I, Fraser N, Giles H. Br J Pharmacol. 2000 Mar;129(5):877-86.