IOX 2

Name IOX 2
Supplier Tocris Bioscience
Catalog 4464
Prices $209.00, $879.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 931398-72-0
Chemical Name N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine
Formula C19H16N2O5
Molecular Weight 352.34
Purity >99 %
Description Potent inhibitor of HIF-1 α prolyl hydroxylase-2 (PHD2) (IC 50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.
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