Name | IOX 2 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4464 |
Prices | $209.00, $879.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 931398-72-0 |
Chemical Name | N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine |
Formula | C19H16N2O5 |
Molecular Weight | 352.34 |
Purity | >99 % |
Description | Potent inhibitor of HIF-1 α prolyl hydroxylase-2 (PHD2) (IC 50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable. |
Supplier Page | Shop |