| Name | IQ 1S |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4713 |
| Prices | $179.00, $745.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1421610-21-0 |
| Chemical Name | 11H-Indeno[1,2-b]quinoxalin-11-oneoximesodiumsalt |
| Formula | C15H8N3NaO |
| Molecular Weight | 269.23 |
| Purity | >99 % |
| Description | JNK inhibitor (K d values are 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Inhibits LPS-induced proinflammatory cytokine and nitric oxide production in vitro . Attenuates collagen-induced arthritis severity and inhibits murine delayed-type hypersensitivity in vivo . Anti-inflammatory and immunosuppressive. Also releases NO upon metabolism by liver microsomes. |
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