IRAK1/4 Inhibitor I

• Supplier: Tocris Bioscience
• Catalog: 4550
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 509093-47-4
• Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide
• Formula: C20H21N5O4
• Molecular Weight: 395.41
• Purity: >98 %
• Description: IRAK4 and IRAK1 inhibitor (IC 50 values are 0.2 and 0.3 μ M, respectively).

Product References

ZD1839 ('Iressa') as an anticancer agent. - ZD1839 ('Iressa') as an anticancer agent.

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Antitumor effect and potentiation of cytotoxic drugs activity in human cancer - Antitumor effect and potentiation of cytotoxic drugs activity in human cancer

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Tumor penetration of gefitinib (Iressa), an epidermal growth factor receptor - Tumor penetration of gefitinib (Iressa), an epidermal growth factor receptor

McKillop D, Partridge EA, Kemp JV, Spence MP, Kendrew J, Barnett S, Wood PG, Giles PB, Patterson AB, Bichat F, Guilbaud N, Stephens TC. Mol Cancer Ther. 2005 Apr;4(4):641-9.