IRL-1620

• Supplier: Tocris Bioscience
• Catalog: 1195
• Prices: $189.00
• Sizes: 500 µg
• Function Type: Agonist
• Cas Number: 142569-99-1
• Formula: C86H117N17O27
• Molecular Weight: 1820
• Description: Highly selective ET B endothelin receptor agonist (K i values are 0.016 and 1900 nM at ET B and ET A receptors respectively). Discriminates two subpopulations of ET B receptors.

Product References

A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, - A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620,

Takai M, Umemura I, Yamasaki K, Watakabe T, Fujitani Y, Oda K, Urade Y, Inui T, Yamamura T, Okada T. Biochem Biophys Res Commun. 1992 Apr 30;184(2):953-9.

Endothelin: progress in pharmacology and physiology. - Endothelin: progress in pharmacology and physiology.

Haynes WG, Davenport AP, Webb DJ. Trends Pharmacol Sci. 1993 Jun;14(6):225-8.

Distinct subdomains of human endothelin receptors determine their selectivity to - Distinct subdomains of human endothelin receptors determine their selectivity to

Sakamoto A, Yanagisawa M, Sawamura T, Enoki T, Ohtani T, Sakurai T, Nakao K, Toyo-oka T, Masaki T. J Biol Chem. 1993 Apr 25;268(12):8547-53.

Suc-[Glu9,Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of - Suc-[Glu9,Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of

Mazzoni MR, Breschi MC, Ceccarelli F, Lazzeri N, Giusti L, Nieri P, Lucacchini A. Br J Pharmacol. 1999 Jul;127(6):1406-14.