Isoproterenol hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 0897
• Prices: $95.00
• Sizes: 100 mg
• Function Type: Agonist
• Cas Number: 51-30-9
• Chemical Name: 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediolhydrochloride
• Formula: C11H17NO3.HCl
• Molecular Weight: 247.72
• Purity: >97 %
• Description: Standard selective β -adrenoceptor agonist; vasorelaxant and bronchodilator. Activation of β 2 receptors activates downstream PKA and ERK, and may stimulate NO-mediated endothelium-dependent smooth muscle relaxation. Active in vivo . Also available as part of the β -Adrenoceptor Agonist Tocriset™ and Mixed Adrenergic Tocriset™ .

Product References

Characterization of the adrenoreceptor activities of isoprenaline in the field - Characterization of the adrenoreceptor activities of isoprenaline in the field

Lotti VJ, Cerino D, Kling P. J Auton Pharmacol. 1982 Sep;2(3):169-74.

beta 2-adrenergic receptor activates extracellular signal-regulated kinases - beta 2-adrenergic receptor activates extracellular signal-regulated kinases

Schmitt JM, Stork PJ. J Biol Chem. 2000 Aug 18;275(33):25342-50.

Nitric oxide (NO) primarily accounts for endothelium-dependent component of - Nitric oxide (NO) primarily accounts for endothelium-dependent component of

Akimoto Y, Horinouchi T, Shibano M, Matsushita M, Yamashita Y, Okamoto T, Yamaki F, Tanaka Y, Koike K. J Smooth Muscle Res. 2002 Oct;38(4-5):87-99.