IT 901

Name IT 901
Supplier Tocris Bioscience
Catalog 4439
Prices $185.00, $779.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1584121-99-2
Chemical Name 5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
Formula C17H14N2O4S
Molecular Weight 342.37
Purity >98 %
Description c-Rel inhibitor (IC 50 = 3 μ M). Inhibits IL-2 expression in activated T-cells in vitro . Reduces severity of graft-versus-host disease following hematopoietic stem cell transplant (HSCT) and inhibits growth of human B-cell lymphoma xenografts in mice. Inhibits the oxidative stress response in lymphoma cells.
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