| Name | ITH 12575 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1803 |
| Prices | $189.00, $795.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1802013-08-6 |
| Chemical Name | 7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one |
| Formula | C18H18ClNOS |
| Molecular Weight | 331.86 |
| Purity | >98 % |
| Description | Mitochondrial Na + /Ca 2+ exchange (mNCX) inhibitor. Reduces Ca 2+ efflux from the mitochondria to the cytosol in HeLa cells (EC 50 = 0.69 μ M). Protects against glutamate-induced excitotoxitiy in rat hippocampal slices and oligomycin A/rotenone induced oxidative stress in neuroblastoma cells in vitro . |
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