| Name | IWP 12 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5156 |
| Prices | $195.00, $805.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 688353-45-9 |
| Chemical Name | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]acetamide |
| Formula | C18H18N4O2S3 |
| Molecular Weight | 418.56 |
| Purity | >98 % |
| Description | Potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC 50 = 15 nM). Inhibits Wnt/ β -catenin and Wnt/planar cell polarity (PCP) signaling pathways. Blocks zebrafish tailfin regeneration in vivo . |
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