| Name | IWP L6 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5214 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1427782-89-5 |
| Chemical Name | N-(5-Phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide |
| Formula | C25H20N4O2S2 |
| Molecular Weight | 472.58 |
| Purity | >98 % |
| Description | Potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (EC 50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys. |
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