JMV 390-1

• Supplier: Tocris Bioscience
• Catalog: 2677
• Prices: $115.00
• Sizes: 1 mg
• Function Type: Inhibitor
• Cas Number: 148473-36-3
• Chemical Name: N-[(2R)-4-Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-isoleucyl-L-leucine
• Formula: C23H35N3O6
• Molecular Weight: 449.54
• Description: Inhibitor of the major neurotensin and neuromedin N degrading enzymes (IC 50 values are 31, 40, 52 and 58 nM for endopeptidase 24.15, endopeptidase 24.11, leucine aminopeptidase and endopeptidase 24.16 respectively). Exhibits analgesic effects in various nociception assays.

Product References

Effects of thiorphan, bestatin and a novel metallopeptidase inhibitor JMV 390-1 - Effects of thiorphan, bestatin and a novel metallopeptidase inhibitor JMV 390-1

Kitabgi P, Dubuc I, Nouel D, Costentin J, Cuber JC, Fulcrand H, Doulut S, Rodriguez M, Martinez J. Neurosci Lett. 1992 Aug 17;142(2):200-4.

Synthesis and analgesic effects of N-[3-[(hydroxyamino) - Synthesis and analgesic effects of N-[3-[(hydroxyamino)

Doulut S, Dubuc I, Rodriguez M, Vecchini F, Fulcrand H, Barelli H, Checler F, Bourdel E, Aumelas A, Lallement JC, et al.. J Med Chem. 1993 May 14;36(10):1369-79.

The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by - The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by

Menard A, Papini E, Mock M, Montecucco C. Biochem J. 1996 Dec 1;320 ( Pt 2):687-91.