JNJ 303

Name JNJ 303
Supplier Tocris Bioscience
Catalog 3352
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Function Type Blocker
Cas Number 878489-28-2
Chemical Name 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide
Formula C21H29ClN2O4S
Molecular Weight 440.98
Purity >98 %
Description Potent I Ks blocker (IC 50 = 64 nM). Displays no effects on other cardiac channels; IC 50 values are 3.3, >10, 11.1 and 12.6 μ M for I Na , I Ca , I to and I Kr currents respectively. Prolongs QT and causes unprovoked torsades de pointes (TdP).
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