| Name | JNJ 5207787 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5299 |
| Prices | $255.00, $1,025.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 683746-68-1 |
| Chemical Name | (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide |
| Formula | C32H38N4O2 |
| Molecular Weight | 510.67 |
| Purity | >98 % |
| Description | Selective NPY Y 2 antagonist (IC 50 = 0.1 μ M). Displays 100-fold selectivity over NPY Y 1 , Y 4 and Y 5 receptors; also displays selectivity against a panel of 50 receptors, ion channels and transporters. Brain penetrant. |
| Supplier Page | Shop |
Bonaventure P, Nepomuceno D, Mazur C, Lord B, Rudolph DA, Jablonowski JA, Carruthers NI, Lovenberg TW. J Pharmacol Exp Ther. 2004 Mar;308(3):1130-7. Epub 2003 Nov 14.
Jablonowski JA, Chai W, Li X, Rudolph DA, Murray WV, Youngman MA, Dax SL, Nepomuceno D, Bonaventure P, Lovenberg TW, Carruthers NI. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1239-42.