JWH 133

• Supplier: Tocris Bioscience
• Catalog: 1342
• Prices: $249.00
• Sizes: 10 mg
• Function Type: Agonist
• Cas Number: 259869-55-1
• Chemical Name: (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
• Formula: C22H32O
• Molecular Weight: 312.49
• Purity: >98 %
• Description: Potent CB 2 selective agonist (K i = 3.4 nM). Approx. 200-fold selective over CB 1 receptors. Active in vivo , reducing spasticity in a murine model of multiple sclerosis. Activity also enhances the release of IL-10 by LPS/IFN- γ -stimulated macrophages and results in downregulation of the IL-12 subunit p40. Also available in water soluble emulsion (Cat. No. 1783).

Product References

3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of - 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of

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Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production - Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production

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