| Name | JX 06 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1783 |
| Prices | $75.00, $315.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 729-46-4 |
| Chemical Name | Bis(morpholinothiocarbonyl)disulfide |
| Formula | C10H16N2O2S4 |
| Molecular Weight | 324.51 |
| Purity | >98 % |
| Description | Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC 50 values are 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively). Exhibits selectivity for PDK1/2/3 over PDK4 and a panel of 323 other kinases. Suppresses A549 lung cancer cell proliferation in vitro . Reduces tumor volume of A549 xenografts in mice. |
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