Ketoconazole

• Supplier: Tocris Bioscience
• Catalog: 0908
• Prices: $115.00
• Sizes: 100 mg
• Function Type: Inhibitor
• Cas Number: 65277-42-1
• Chemical Name: cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
• Formula: C26H28Cl2N4O4
• Molecular Weight: 531.44
• Purity: >99 %
• Description: Antifungal agent; potent inhibitor of cytochrome P450c17.

Product References

Inhibition of human adrenal steroidogenic enzymes in vitro by imidazole drugs - Inhibition of human adrenal steroidogenic enzymes in vitro by imidazole drugs

Ayub M, Levell MJ. J Steroid Biochem. 1989 Apr;32(4):515-24.

Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect - Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect

Kuhn-Velten WN, Lessmann M. Biochem Pharmacol. 1992 Dec 15;44(12):2371-8.

Blockade of HERG and Kv1.5 by ketoconazole. - Blockade of HERG and Kv1.5 by ketoconazole.

Dumaine R, Roy ML, Brown AM. J Pharmacol Exp Ther. 1998 Aug;286(2):727-35.