| Name | KG 5 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2748 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 877874-85-6 |
| Chemical Name | 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine |
| Formula | C20H16F3N7OS |
| Molecular Weight | 459.45 |
| Purity | >98 % |
| Description | PDGFR β and B-Raf allosteric inhibitor. Also inhibits c-Raf, FLT3 and KIT. Disrupts blood vessel formation in zebrafish embryos and inhibits angiogenesis in a mouse angiogenesis model. Inhibits growth of renal and pancreatic tumors in mice. Also arrests cells in prometaphase. Orally available. |
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