Kisspeptin 10 (human)

• Supplier: Tocris Bioscience
• Catalog: 5347
• Prices: $279.00
• Sizes: 1 mg
• Cas Number: 374675-21-5
• Formula: C63H83N17O14
• Molecular Weight: 1302.45
• Description: Potent endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with K i values of 1.59 and 2.33 nM respectively. Inhibits metastasis and invasion in mouse melanomas and stimulates gonadotropin secretion following i.c.v. administration.

Product References

The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of - The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of

Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Le Poul E, Brezillon S, Tyldesley R, Suarez-Huerta N, Vandeput F, Blanpain C, Schiffmann SN, Vassart G, Parmentier M. J Biol Chem. 2001 Sep 14;276(37):34631-6. Epub 2001 Jul 16.

Kisspeptin acts directly and indirectly to increase gonadotropin-releasing - Kisspeptin acts directly and indirectly to increase gonadotropin-releasing

Pielecka-Fortuna J, Chu Z, Moenter SM. Endocrinology. 2008 Apr;149(4):1979-86. Epub 2007 Dec 27.