| Name | KU 0063794 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4840 |
| Prices | $245.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 938440-64-3 |
| Chemical Name | rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol |
| Formula | C25H31N5O4 |
| Molecular Weight | 465.54 |
| Purity | >97 % |
| Description | Selective inhibitor of mammalian target of rapamycin (mTOR) (IC 50 ~10 nM for mTORC1 and mTORC2). Displays no activity at PI 3-kinase or 76 other kinases tested. Inhibits activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK. Suppresses cell growth and induces G 1 cell cycle arrest in vitro . |
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