KU14R

• Supplier: Tocris Bioscience
• Catalog: 4176
• Prices: $139.00, $579.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 189224-48-4
• Chemical Name: 2-(2-Ethyl-2,3-dihydro-2-benzofuranyl)-1H-imidazole
• Formula: C13H14N2O
• Molecular Weight: 214.27
• Purity: >99 %
• Description: Antagonist of the atypical imidazoline binding site (putative I 3 receptor) of pancreatic β -cells. Selectively blocks efaroxan-induced insulin secretion in vitro and in vivo .

Product References

The effect of the putative endogenous imidazoline receptor ligand, - The effect of the putative endogenous imidazoline receptor ligand,

Chan SL, Atlas D, James RF, Morgan NG. Br J Pharmacol. 1997 Mar;120(5):926-32.

Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in - Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in

Chan SL, Pallett AL, Morgan NG. Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):763-8.

Effects of the imidazoline ligands efaroxan and KU14R on blood glucose - Effects of the imidazoline ligands efaroxan and KU14R on blood glucose

Mayer G, Taberner PV. Eur J Pharmacol. 2002 Nov 1;454(1):95-102.