Kynurenic acid

• Supplier: Tocris Bioscience
• Catalog: 5290
• Prices: $75.00
• Sizes: 1 g
• Function Type: Antagonist
• Cas Number: 492-27-3
• Chemical Name: 4-Hydroxyquinoline-2-carboxylicacid
• Formula: C10H7NO3
• Molecular Weight: 189.17
• Purity: >98 %
• Description: Broad spectrum EAA antagonist. Putative GPR35 ligand. Kynurenic acid sodium salt also available (Cat. No. 3694).

Product References

An iontophoretic investigation of the actions of convulsant kynurenines and their - An iontophoretic investigation of the actions of convulsant kynurenines and their

Perkins MN, Stone TW. Brain Res. 1982 Sep 9;247(1):184-7.

NMDA receptors and ligands in the vertebrate CNS. - NMDA receptors and ligands in the vertebrate CNS.

Stone TW, Burton NR. Prog Neurobiol. 1988;30(4):333-68.

The "kynurenate test", a biochemical assay for putative cognition enhancers. - The "kynurenate test", a biochemical assay for putative cognition enhancers.

Pittaluga A, Vaccari D, Raiteri M. J Pharmacol Exp Ther. 1997 Oct;283(1):82-90.

Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. - Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.

Wang J, Simonavicius N, Wu X, Swaminath G, Reagan J, Tian H, Ling L. J Biol Chem. 2006 Aug 4;281(31):22021-8. Epub 2006 Jun 5.