L-701,252

• Supplier: Tocris Bioscience
• Catalog: 0781
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 151057-13-5
• Chemical Name: 7-Chloro-3-(cyclopropylcarbonyl)-4-hydroxy-2(1H)-quinolinone
• Formula: C13H10ClNO3
• Molecular Weight: 263.68
• Purity: >99 %
• Description: An antagonist at the glycine-NMDA site (IC 50 = 420 nM). Also a potent systemic anticonvulsant.

Product References

3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting - 3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting

Rowley M, Leeson PD, Stevenson GI, Moseley AM, Stansfield I, Sanderson I, Robinson L, Baker R, Kemp JA, Marshall GR, et al.. J Med Chem. 1993 Oct 29;36(22):3386-96.

Development and therapeutic potential of kynurenic acid and kynurenine - Development and therapeutic potential of kynurenic acid and kynurenine

Stone TW. Trends Pharmacol Sci. 2000 Apr;21(4):149-54.