L-701,324

• Supplier: Tocris Bioscience
• Catalog: 0705
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Cas Number: 142326-59-8
• Chemical Name: 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone
• Formula: C21H14ClNO3
• Molecular Weight: 363.8
• Purity: >99 %
• Description: An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor.

Product References

3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally - 3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally

Kulagowski JJ, Baker R, Curtis NR, Leeson PD, Mawer IM, Moseley AM, Ridgill MP, Rowley M, Stansfield I, Foster AC, et al.. J Med Chem. 1994 May 13;37(10):1402-5.

The atypical neuroleptic profile of the glycine/N-methyl-D-aspartate receptor - The atypical neuroleptic profile of the glycine/N-methyl-D-aspartate receptor

Bristow LJ, Flatman KL, Hutson PH, Kulagowski JJ, Leeson PD, Young L, Tricklebank MD. J Pharmacol Exp Ther. 1996 May;277(2):578-85.

Anticonvulsant and behavioral profile of L-701,324, a potent, orally active - Anticonvulsant and behavioral profile of L-701,324, a potent, orally active

Bristow LJ, Hutson PH, Kulagowski JJ, Leeson PD, Matheson S, Murray F, Rathbone D, Saywell KL, Thorn L, Watt AP, Tricklebank MD. J Pharmacol Exp Ther. 1996 Nov;279(2):492-501.

Inhibition of cortical spreading depression by L-701,324, a novel antagonist at - Inhibition of cortical spreading depression by L-701,324, a novel antagonist at

Obrenovitch TP, Zilkha E. Br J Pharmacol. 1996 Mar;117(5):931-7.